#020 Sally Norton - Oxalates, Toxins & The Truth About 'Healthy' Foods
Sally K. Norton, MPH, is a nutrition educator and consultant specialising in the impact of dietary oxalates on health. She earned her Bachelor of Science in Nutrition from Cornell University and a Master of Public Health from the University of North Carolina at Chapel Hill. Throughout her career, Sally has held significant roles in medical education, public health research, and holistic healing. Notably, she managed a five-year, NIH-funded program at UNC Medical School, focusing on educating students and faculty about integrative healing practices. Her personal health challenges led her to explore the effects of oxalates in plant-based diets, culminating in her acclaimed book, “Toxic Superfoods: How Oxalate Overload Is Making You Sick—and How to Get Better.” Sally is dedicated to raising awareness about oxalate toxicity and offers guidance on adopting low-oxalate diets to improve overall well-being. Her expertise has been featured across various media platforms, and she continues to provide consultations and educational resources through her website.
> During our discussion, you’ll discover:
(00:04:09) What are oxalates
(00:09:18) Why do we have oxalates in our body
(00:10:53) Do plants have a place in our diet
(00:22:24) How oxalates damage mitochondria
(00:31:28) The link between oxalate overload and other medical issues
(00:38:18) How can you be sure that oxalates are the issue
(00:44:24) Is there a relationship between oxalates and fungal infections
(00:45:46) Oxalate testing
(00:49:44) How to start getting rid of oxalates safely
(00:56:39) Supplements
(01:03:43) Why are oxalate issues not talked about more
(01:04:57) What is 1 food people don’t know cause oxalate issues
(01:06:23) The most common misconceptions about oxalates
(01:07:04) Sally’s thoughts on the carnivore diet
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Research Notes:
Transcript
Welcome to the VP Life Podcast, the show where we bring you actionable
Speaker:health advice from leading minds.
Speaker:I'm your host, Rob.
Speaker:My guest today is Sally Norton.
Speaker:Sally is nutritional consultant and oxalate educator who's on a mission
Speaker:to educate the world at large on the potential dangers of oxalates.
Speaker:Expect to learn what oxalates are and what foods they're commonly found
Speaker:in, how oxalates can damage cells and drive disease, and the best strategies
Speaker:to detox from oxalates safely.
Speaker:Now onto the conversation with Sally Norton.
Speaker:Good morning Sally, and thank you for joining us today.
Speaker:I'm very familiar with your work and so I'm excited and honored to have
Speaker:this opportunity to chat with you.
Speaker:Uh, I know you've been fairly popular on the podcast circuit as of late,
Speaker:and while most in the holistic health space are likely familiar with you
Speaker:and your work, there will be those who maybe aren't as familiar with you, uh,
Speaker:especially in our audience over in the uk.
Speaker:Would you mind introducing yourself and running us through your story?
Speaker:Well, I have been a, a nutrition geek since kindergarten, since I
Speaker:was a little preschooler, long time interest in trying to be healthy.
Speaker:And in middle school when I was about 12, I had this insight in science
Speaker:classes like, oh, you mean you can avoid major chronic diseases potentially
Speaker:because nutrition has a major role in whether you get really sick and a
Speaker:major role in prevention of disease.
Speaker:And so I've been trying to do well since I was a little child,
Speaker:eat just the right things.
Speaker:And unfortunately I did everything right but struggled with health
Speaker:problems from early on in life.
Speaker:And it became disabling in college, in graduate school and again and again,
Speaker:over and over again, I'm running into major problems that are interrupting
Speaker:my career and I was at a loss for answers and I'm in my late forties.
Speaker:I'm an expert in holistic and I healthy living and and therapies
Speaker:and integrative medicine and.
Speaker:Public health and nutrition, successful aging.
Speaker:And I didn't know what was wrong with me and neither did my colleagues in
Speaker:functional medicine and holistic healing and standard medicine nobody was giving,
Speaker:pointing me to the answer until one symptom in 2009 pointed me to an outfit
Speaker:online called the Vulva Pain Foundation.
Speaker:Vulva Pain is a gen genital pain burning that ruins your life, and it took me
Speaker:another nearly four years to really have this breakthrough insight that brought
Speaker:me into this mind bending realization that led me to more and more surprises
Speaker:as I started to get better by taking out my lifetime of spinach bee greens.
Speaker:It was really Swiss chard, sweet potatoes, and holy cow, all kinds of old
Speaker:problems started unwinding themselves.
Speaker:So I talk about this.
Speaker:In my book, toxic Superfoods, and on my website on the about page, there's a
Speaker:little summary of, wow, it took, I had to really get over all the knowingness of all
Speaker:my knowledge and be desperate enough to recognize that the enemy was right on my
Speaker:plate and my organic garden in my kitchen.
Speaker:Wow.
Speaker:Yeah.
Speaker:Yeah.
Speaker:Talk about being fed a lie.
Speaker:I think, uh, I came up with that on this, sorry.
Speaker:That's my best joke for the day.
Speaker:Unfortunately, we're feeding lies to pregnant women and babies too.
Speaker:I mean, this is, we can kind of laugh at our own suffering and go, oh,
Speaker:well, at least she made it to her sixties and got through that somehow.
Speaker:But if only we had known this earlier in my life, and only if
Speaker:we can now help others because.
Speaker:We're in an age now with the foods that we're supplying this damage to
Speaker:my life are universally revered and trusted and assumed to be innocent.
Speaker:Yeah.
Speaker:And, and I think that's definitely, uh, a point we'll
Speaker:get onto later on in the podcast.
Speaker:Thank you for that.
Speaker:Your star.
Speaker:I reckon we should, we might as well get into the, the meat and
Speaker:potatoes or I suppose the spinach might be applicable of, of today's
Speaker:conversation, um, which is oxalates.
Speaker:And, uh, um, we've obviously, you've already already alluded to them, uh, but
Speaker:at a high level, could you explain to the audience what exactly oxalates are?
Speaker:Um, I know you've mentioned some food sources already, but what are these,
Speaker:uh, these plant chemicals that seem to pose such an issue for so many people?
Speaker:Right.
Speaker:So plants make this oxalic acid.
Speaker:Oxalic acid is a small little molecule.
Speaker:It's a chelating acid.
Speaker:Two little carbons with four oxygen, which is really interesting.
Speaker:And it's so heavily oxygenated.
Speaker:It's really di carbolic acid.
Speaker:So this thing likes to grab positively charged ions like calcium, magnesium.
Speaker:All the minerals out there tend to get bound up with oxalic acid.
Speaker:And then we call that an oxalate when it's in connection with a metal.
Speaker:And these oxalates form bonds with each other.
Speaker:Little pairs of them, groups of pairs.
Speaker:About eight or 12 pairs come together and they form nano crystals.
Speaker:This is crystallization and start to build into crystals.
Speaker:Those crystals are commonly seen in kidney stones.
Speaker:So oxalic acid, that's plants make soils, make it from the, the
Speaker:fungus and so on in the soils.
Speaker:It even is made.
Speaker:It's so easy to make it in nature.
Speaker:Clouds with a little bit of pollution and moisture will form oxalic acid.
Speaker:We've had a problem here in the Eastern United States.
Speaker:Uh.
Speaker:Acid rain.
Speaker:It turns out oxalic acid is the major acid in acid rain, and it melts monuments and
Speaker:causes problems with soil pH and so on.
Speaker:So it's everywhere.
Speaker:It's ubiquitous in nature.
Speaker:A lot of plants make it so much of it that they're completely inedible.
Speaker:And then there's the ones we've bred for the produce aisle, which have less.
Speaker:But some of those we cannot seem to breed well enough to get them
Speaker:low enough to really be safe.
Speaker:And somehow we're ignoring it.
Speaker:So yeah, oxalic acid, oxalates, it's set in the plural.
Speaker:It forms these different forms from an acid to a molecule to a crystal.
Speaker:Different kinds of minerals can be connecting to it, and it can
Speaker:change places and move around.
Speaker:So we call 'em oxalates, plural.
Speaker:We're talking kind of generally about crystals and an acid, a free acid,
Speaker:and they have different properties and different tendencies in the bodies.
Speaker:So it's important to kind of know there's this soluble acid.
Speaker:And then there's these insoluble calcium oxalate crystals, which
Speaker:become a crystallization in the body.
Speaker:Yeah.
Speaker:And are, are the, are oxalates, uh, I suppose produced at all in
Speaker:the human body in endogenously.
Speaker:Do do you humans produce these, these molecules or do they just come from diet?
Speaker:Well, they, you can eat it directly in the foods that are all plant
Speaker:foods, animal foods don't have it.
Speaker:And then there's the, the transformation of precursor molecules into oxalic acid.
Speaker:And that does occur in the body to a small degree.
Speaker:We produce about an average of 12 milligrams daily in this
Speaker:sort of endogenous process.
Speaker:But the very interesting thing about it, if you understand what these
Speaker:precursor molecules are that become oxalate, you realize the big one that's
Speaker:producing more than half, probably at least 40%, maybe much more than
Speaker:that, of this endogenous production.
Speaker:This little 12 milligrams is coming from vitamin C supplementation.
Speaker:Oh yeah, no, and I think there are a bunch of other, uh, offending
Speaker:supplements out there, such as glycine that can also contribute as well.
Speaker:As far as know, glycine is
Speaker:not so bad.
Speaker:It's a pretty small amount.
Speaker:It's a hydroxyproline is worse, which is in collagen.
Speaker:So if you're using whole collagen and you're using more than maybe four
Speaker:teaspoons a day, which is, what is that?
Speaker:Um,
Speaker:20 grams or so?
Speaker:20 mils, yeah.
Speaker:So that's enough to start generating more oxalate in the body, but it's
Speaker:still a relatively small amount.
Speaker:But you can, people literally can feel the difference when they quit overdoing
Speaker:the collagen supplements or they stop the vitamin C. Those two things can be
Speaker:major ways of protecting yourself from this so-called endogenous production.
Speaker:But to me, if it's coming from something you're eating and have
Speaker:an option to not eat, I. That's not really endogenous production so much
Speaker:just because the transformation's occurring inside the body.
Speaker:So it's kind of a misnomer that's been abused by people who wanna just be, have
Speaker:carte blanche to eat what they want.
Speaker:Ah, your body's making it anyway, so what?
Speaker:Well, with toxins, your body does make toxins.
Speaker:That's why you pee it out.
Speaker:That's why you make feces.
Speaker:That's why you peel off your skin and you sweat and you have, you have lymph
Speaker:glands and all this stuff because you're moving toxins outta the body.
Speaker:Even the fluids from the eyes, you are moving toxins outta the body.
Speaker:Of course, the body both receives and creates tox, toxins, but it
Speaker:doesn't mean that gives you permission to start picking out on toxins.
Speaker:Yeah, of course.
Speaker:Yeah.
Speaker:I suppose that sort of does, that sort of almost begs the question, is there any.
Speaker:Reliable data on why we have oxalate in the body.
Speaker:Uh, is that something you know of hand Maybe.
Speaker:Is there a sort of a place, is there a biological requirement for oxalate at any
Speaker:level or is it something that we ju is it purely something that is introduced
Speaker:to our diet that shouldn't be there, that causes more problems than it's worth?
Speaker:Right.
Speaker:So this is a, a potentially complex conversation because we see, we see
Speaker:sort of free radical production by mitochondria as signaling molecules that
Speaker:helps the body make more glutathione and start fighting back and do good things.
Speaker:So there sometimes something that's too much of it is bad, a little bit is
Speaker:good, and the right environment is good.
Speaker:So is a little bit of oxalate good or not?
Speaker:It, it's never shown up as being a signaling molecule that's creating
Speaker:some kind of defense response.
Speaker:And the only possible advantage that I've seen is that the oxalate
Speaker:that's concentrated in the saliva.
Speaker:Might actually form a tartar on the teeth that's somewhat protective.
Speaker:Okay, good.
Speaker:But in the, in the mitochondria, in the cells, they would do fine
Speaker:without something that's ruining the membranes and interfering with enzyme
Speaker:production or enzyme function and causing all kinds of, um, oxidative
Speaker:stress using glutathione against.
Speaker:There haven't, there isn't really, um, there are people who wish
Speaker:there was, and they're not the real scientists who are saying, well,
Speaker:we don't see it.
Speaker:You've already answered this in a sense, but I'd love to clear, get a,
Speaker:excuse me, a clearer picture here.
Speaker:Um, as I've alluded to earlier, I've listened to several of your
Speaker:conversations you've had recently, especially with individuals, um, with
Speaker:let's say more restrictive ideas and ideologies when it comes to diets.
Speaker:So your Anthony Chaffee of the world who are obviously fairly firm
Speaker:believers, uh, in the idea that plants.
Speaker:All of them are, are trying to kill us.
Speaker:Um, now I do think a carnival diet is definitely a useful tool, um, for certain
Speaker:people at certain times of in their lives and, and that it can be very effective
Speaker:as an elimination diet and all of that.
Speaker:Um, I suppose this is a bit of a broader question, but where
Speaker:do you stand on the spectrum?
Speaker:Do you feel, uh, that we should be getting rid of most plant
Speaker:matter for the whole part?
Speaker:Um, or do do plants have a, a place in the human diet?
Speaker:Uh, I suppose what I'm asking is are vegetables trying to kill us?
Speaker:Well, you know, we don't necessarily wanna do a prescription for all of humanity yet,
Speaker:but if we're thinking just generally in principles about what is humanity meant
Speaker:to be eating and what's really optimizes health versus what you can get away with,
Speaker:I mean, there's all kinds of angles you could take to these questions if you're
Speaker:interested in optimization and protecting.
Speaker:The health of the future generations.
Speaker:And you're really interested in seeing functional longevity, not just hospital
Speaker:based longevity and drug supported fake longevity, but actual vital
Speaker:functioning, healthy, full life, living up to the some nice rip mature age.
Speaker:There's a lot of questions there about whether plants at all necessary.
Speaker:Can you live that optimal life and can you produce healthy generations
Speaker:going forward without plants?
Speaker:And there's evidence that you can, there's, there's peoples on this
Speaker:earth who've lived in areas that don't have any plants like the ice poles.
Speaker:The northern, the northern regions of Alaska and that kind of place do have done
Speaker:pretty well without much plants at all.
Speaker:And, uh, certain tribals, people like the Messiah traditionally in the
Speaker:old days would have very few plants.
Speaker:So we know that human beings.
Speaker:Don't necessarily have to have plants to be healthy.
Speaker:And that in itself is a huge controversial idea because we've
Speaker:been told in modern life that plants have essential planty stuff.
Speaker:These phytonutrients, you gotta have 'em, they're gonna give you
Speaker:longevity and all this stuff.
Speaker:But that is based, that is standing on a pillar of jello.
Speaker:'cause we came up with this idea that there were these antioxidants in plants
Speaker:as a back of the envelope placeholder.
Speaker:That hasn't held up at all.
Speaker:They have not been able to demonstrate any kind of consistent way where, say
Speaker:polyphenols or whatever, consistently in all people have this beneficial effect.
Speaker:And if and when it has a beneficial effect, it's because it's interacting
Speaker:luckily with certain genetics and certain microbiome in the colon.
Speaker:And if you don't have those genetics in that microbiome and you don't know
Speaker:which ones to use, there's tens of thousands of polyphenols and so on.
Speaker:We, we have no way to actually use that concept effectively for all people.
Speaker:Um, and what's happening is that we have this selective idea
Speaker:of this benefits only mindset.
Speaker:So there might be something great in plants, maybe sometimes,
Speaker:probably, okay, but which ones?
Speaker:How much?
Speaker:And so on.
Speaker:We've got this blind spot around.
Speaker:Well, what about the antinutrients implants?
Speaker:Toxic chemicals, generally, their effect on illness and aging has
Speaker:been overlooked for a long time.
Speaker:In general, by everyone excluding science and with oxalate.
Speaker:Science is very familiar with the toxicity of oxalate and yet clueless about the
Speaker:impact of oxalate in our foods, on our health in the short, in the long
Speaker:run on reproductive health and so on.
Speaker:And modern research is so over focused on kidney stones and they have an agenda
Speaker:that would have them pretend We don't know that diet is supplying the required
Speaker:material to become kidney stones.
Speaker:If you say that, then why do you need funding forevermore?
Speaker:Why do you need to captivate all funding and oxalates for 70 years
Speaker:when you're busy pretending it's not made of the stuff you're eating?
Speaker:And we know that the diet is the main cause of that.
Speaker:So there's a lot of things around us that are affecting our viewpoint about diet.
Speaker:Personally, I do think plants have a right to take care of themselves in a,
Speaker:you know, we ourselves, we need to be less disneyfied in our thinking, like
Speaker:we have to be a little more logical.
Speaker:You have to think the science is not a Disney movie or Nature's not
Speaker:a Disney movie, but nature is claws, lightning, fire, death, destruction,
Speaker:hurricanes, you know, such a nice place.
Speaker:Nature's a rough place.
Speaker:Yeah.
Speaker:So Oxalate is a tool harnessed by plants brilliantly for their
Speaker:own survival and self-defense.
Speaker:They cannot afford to play nicey nicey like they do in Disney movies.
Speaker:They have to take care of business and survive.
Speaker:If they were completely non-toxic, they'd be extinct.
Speaker:Yeah.
Speaker:And what do you think about fruits in that regard?
Speaker:Uh, I mean, fruits, uh, have a, uh, a different sort of biological imperative.
Speaker:I mean, they, they contain seeds.
Speaker:They, uh, the idea being, they're obviously that they sort of, the aim is
Speaker:for them to be ingested so that those seeds can then be, uh, dispersed across
Speaker:the landscape and, and that plant can, well, in this case, that fruit can then
Speaker:seed and, and produce more offspring.
Speaker:Um, do you think fruits carry the same level of, of, of issues
Speaker:potentially That is, well, you can
Speaker:say the same for nuts too, because nuts are, um, squirrels and other vermin
Speaker:are very busy, interested in nuts and burying them for the trees and so on.
Speaker:And so trees and plants are using the mobile animal kingdom to support
Speaker:that seed distribution as they use wind and water and other natural
Speaker:tools to dis disperse their seeds.
Speaker:There are plenty of berries on plants that you would never let a child eat because
Speaker:only a bird can survive eating them.
Speaker:So fruits aren't necessarily needing us to survive to have that dis
Speaker:dispersion 'cause there's other creatures helping them disperse.
Speaker:So it's a mixed bag.
Speaker:But for the fruits in the produce aisle that we've bred and bred and bred to
Speaker:make sweeter and more interesting and more full of calories and enjoyment, most
Speaker:of them are okay in terms of oxalate.
Speaker:And the main exceptions are blackberries, kiwis, figs, pomegranate
Speaker:plantain, raspberries is as well.
Speaker:And star fruit is absolutely poisonous.
Speaker:So, but most of the other fruits are fine and the, the fruit.
Speaker:So here's a, a chance to get into the.
Speaker:Geeky nitty gritty distinction and oxalates.
Speaker:Yes, please.
Speaker:So there's soluble oxalic acid and then there's calcium oxalate crystals.
Speaker:And the fruit seems to have the insoluble oxalates.
Speaker:So they're probably very small crystals attached to membranes and fibrous
Speaker:materials, and they're not, probably not as absorbed into the bloodstreams.
Speaker:So the acid moves between cells of the gut and gets into your bloodstream pretty
Speaker:easily and fairly quickly, right up in the stomach and upper small intestine.
Speaker:Whereas this insoluble stuff would take a long time, maybe all
Speaker:the way to the colon before it's available for absorption, if at all.
Speaker:So you don't get as much of it messing with your blood system, your blood
Speaker:cells, your vascular system, and your organs just messing with your gut.
Speaker:So the fruit is more likely to deliver these crystals that are pretty hard
Speaker:hardcore, like the Kiwi has the.
Speaker:The toothpicks shaped crystals, the RAF hides, and these are bundles of
Speaker:hundreds of these little toothpicks with points on both ends that are
Speaker:designed to penetrate the mucosal cells.
Speaker:Two cells deep, but technically the cell lining of your intestinal
Speaker:tract is only one cell deep.
Speaker:So you're eating ground glass when you're eating kiwi and things like
Speaker:this, and that's causing oxidative stress or, or you know, mechanical
Speaker:abrasion, which is a type of toxicity.
Speaker:So it's a different kind of toxicity.
Speaker:So fruits in moderation, no problem, probably.
Speaker:Um, and yeah, I think we need carbs.
Speaker:I think we're drawn to carbs.
Speaker:We have sugar tasting tongue.
Speaker:We're attracted to it.
Speaker:We're designed to eat carbs because that's what the tongue is telling us.
Speaker:You want this sweet stuff, but in nature it just was hard to get carbs because
Speaker:those fruits, uh, in nature aren't as sweet as the ones in the produce aisle.
Speaker:They're not as big and juicy.
Speaker:They're small and bitter and tough and have skin and seeds and.
Speaker:So, yeah, I, you know, if you, depending on what really is the question is, the
Speaker:question is historically ancestrally, were fruits important part of the diet,
Speaker:probably just very seasonal, a little bit of drying of berries and things like that.
Speaker:Not as big a roll as we might like with like bananas and apples
Speaker:everywhere you turn, and bright oranges everywhere that we have now.
Speaker:But I think fruits are, um, a nice way to have flavor and color and vegetables
Speaker:the same way vegetables bring you texture and diversity and color and
Speaker:interest and culinary possibilities.
Speaker:And you can expand that kind of, sort of hedonistic desire to have
Speaker:interesting food, um, has its value.
Speaker:You build culture on that, but it's not necessarily critical to human health.
Speaker:Yeah, I suppose I, I've still yet to sort of come to a conclusion on, on,
Speaker:on the, on the plant side of things.
Speaker:Um, definitely not a microbiologist, I'm a chemist, so I look at it more
Speaker:from a sort of a perspective of fats, uh, carbs and proteins and all of that.
Speaker:And you raise an interesting point where you said you need, uh, well,
Speaker:where, when you said that we need carbohydrates as a species, and I
Speaker:think I, I, I would agree with that.
Speaker:For the most part, I think a lot of people can get away with the ketogenic diet.
Speaker:Um, however, I think for a lot of people being in that sort of long
Speaker:term state, ketosis can potentially have downsides, especially for, for
Speaker:younger women who, who are of, uh.
Speaker:Yeah.
Speaker:Who are, who are of fertile age.
Speaker:Um, I think when you start restricting carbohydrates, you can start
Speaker:increasing, uh, SHBG and th uh, thyroid binding globulin and, and drive and
Speaker:cause all sorts of, uh, endocrine dysfunction, um, as a result of this.
Speaker:Mm-hmm.
Speaker:Over restriction of carbohydrates.
Speaker:So I think for certain groups of people it is def it's definitely required.
Speaker:Um,
Speaker:and you can play with the tool of ketosis Yeah.
Speaker:And go in and out of ketosis.
Speaker:Oh, definitely.
Speaker:And have that metabolic flexibility without having to stay in some
Speaker:deeply the therapeutic, I mean, any therapy that needs to happen every
Speaker:day of your life forevermore doesn't make sense as a therapy anymore.
Speaker:And we lose sight of that.
Speaker:You can have benefits from a certain technique or herb or anything else,
Speaker:but usually the short term value is really where it's at when you
Speaker:start doing something chronically.
Speaker:It has a different effect and sometimes that effect is harmful.
Speaker:Yeah, no, I, I couldn't agree more.
Speaker:Um.
Speaker:You've already touched on it, um, to some extent, but I'd love to sort of go into
Speaker:a little bit more detail with regards to how oxalates are potentially damaging
Speaker:the mitochondria or our mitochondria, the powerhouses of our, of our bodies,
Speaker:and how they are sort of creating this sort of, this, this disruption at a
Speaker:cellular level, um, and creating, uh, an energy deficit within the body.
Speaker:Because I think, uh, based again on my research and my background, ultimately
Speaker:all disease or disease, uh, ends up with these, these organ, these all organelles
Speaker:in the cells becoming ineffective at doing their job, which is to create energy.
Speaker:And obviously there, there are a lot of potential causes, uh, for that.
Speaker:They, they're normally toxin in nature, whether that's mold or another infection.
Speaker:Obviously today, um, we're talking specifically about oxalates and to a
Speaker:larger, to a big extent, I suppose, plant def uh, defense, uh, chemicals, but.
Speaker:Would you mind elaborating again at a relatively high level, obviously, so
Speaker:it's accessible, um, how oxalates are essentially creating this mitochondrial
Speaker:dysfunction and this subsequently this lack of available energy.
Speaker:This is sort of almost a idea of, hello, life is energy.
Speaker:You're not alive without energy, and anything that cuts your energy
Speaker:is cutting back on your life.
Speaker:And this profoundly important to think about energy, energy production,
Speaker:energy availability for your cells.
Speaker:And of course, the mitochondria are the major factories that's managing energy
Speaker:sources and turning them into energy currency that allows your cells to
Speaker:function properly and do all their jobs.
Speaker:And when that currency runs short.
Speaker:The cell's ability to do its job are highly compromised, and then
Speaker:you're on your way to disease.
Speaker:You absolutely need cells that have enough mitochondria that are
Speaker:working well in order to grow, thrive, and maintain your tissues.
Speaker:When your tissues don't make enough energy, they start falling apart.
Speaker:And oxalate is a major energy suck from the body and it's you're eating it and
Speaker:you can't eliminate it through metabolism.
Speaker:You can't metabolize it.
Speaker:You just move it around the body and try to get rid of it.
Speaker:But in the meantime, every tissue is exposed to, or that is exposed to, it
Speaker:is potentially damaging cell membranes, especially if there's a crystal formation
Speaker:going on because there's a charge there.
Speaker:Cell membranes have this double lipid structure and this bilipid layer has
Speaker:a very particular structure where certain molecules are on the inside
Speaker:and certain ones are on the outside.
Speaker:Well, it causes a, a flip where one of the molecules is supposed to be on
Speaker:the inside, only flips to the outside.
Speaker:And this is really quite serious because membranes are where energy is produced.
Speaker:Inside membranes sit, these big proteins, these enzymes in these series of enzymes
Speaker:that are happening on all the membranes.
Speaker:If this, the fatty molecules that make up the membrane are wrong, then
Speaker:the, the proteins themselves that do this work don't work right either.
Speaker:So now you've got a damaged cell membrane, which is the sort of factory
Speaker:walls and floors that allows your factory to do this energy handling.
Speaker:And so you've got membrane changes, you've got oxidation
Speaker:going on, and that's depleting the antioxidant capacity of the cells.
Speaker:So you start using up glutathione and then you're.
Speaker:Own capacity to handle that.
Speaker:Stress goes way down.
Speaker:And so things go from broken to more broken to more broken, and you
Speaker:start damaging proteins, oxidizing the lipids, all these other
Speaker:molecules start to be messed up.
Speaker:The immune system recognizes, starts taking the cells away, but
Speaker:particularly in the mitochondria.
Speaker:So there should have plenty of mitochondria, especially in cells like
Speaker:muscle cells, nerve cells and so on.
Speaker:You're penetrating the mitochondria with this little oxalic acid molecule and
Speaker:messing with the handling of calcium.
Speaker:So the cells have to have very tight control over these ions of calcium.
Speaker:That's an individual molecule with charge, usually two charges on a calcium ion.
Speaker:And this little.
Speaker:This little molecule is a signaling molecule that helps the
Speaker:cell decide what to do when and what it's supposed to be doing.
Speaker:It's very interesting.
Speaker:You have to control that with these sub organelles like the mitochondria
Speaker:and another one called the endoplasmic reticulum and control what's going
Speaker:on between those two organelles with where calcium's moving back and forth.
Speaker:While here you have a calcium chelator that grabs the calcium and causes calcium
Speaker:buildup where it shouldn't be, and calcium depletion and just interferes with the
Speaker:entire communication system in a cell.
Speaker:Um, and then you've got the, the oxalic acid will sit on these enzymes needed to
Speaker:produce energy and to produce glucose.
Speaker:So there's four or five of these.
Speaker:These enzymes that where there's a spot there where the active site, where
Speaker:oxalate fits in there just perfectly.
Speaker:So these pyruvate, um, carboxylase and so on that generate in the first run,
Speaker:when you take glucose and try to turn it into the currency of a TP, you've got
Speaker:this last step that helps produce these ATVs that gets blocked by an oxalate.
Speaker:And then in your electron transport chain down in the mitochondria, you've
Speaker:got complex two and so on and so on.
Speaker:Being interfered with, so you're breaking the machinery itself.
Speaker:So we have this factory, the cell, the floors, the walls are messed
Speaker:up and now you're, the actual equipment is broken through oxalate
Speaker:interfering with enzyme function.
Speaker:So it's kind of a mess.
Speaker:Yeah, so if I was to summarize that for the audience, at a high level,
Speaker:what's happening is that to start off with oxalates getting to the body, uh,
Speaker:then it's essentially, it's damaging the, the cell membrane layer, which is
Speaker:causing almost well the cell to act at a dysfunctional level, but it's also gonna
Speaker:cause, um, altered cellular communication.
Speaker:Um, you're also going to then have, uh, oxalate sort of get into the cell and
Speaker:start interfering with, uh, the cell's ability to utilize calcium properly.
Speaker:Uh, I assume that's through some sort of voltage gated cha uh, calcium
Speaker:channels, something to that extent.
Speaker:Um, and that is then causing either the influx of, of calcium
Speaker:into the cell and damaging a cell.
Speaker:'cause obviously, uh, as you know, if there's too much calcium in
Speaker:the cell, it, it causes, it can call cell death, cell apoptosis.
Speaker:Um.
Speaker:And then beyond that, it's also, uh, at an enzymatic level, it's, it's, it's,
Speaker:uh, causing calcium to, uh, if I follow correctly, to bind to, uh, specific places
Speaker:in the cell that, uh, cause this cause the cell then to not produce energy properly.
Speaker:Uh, would that be a relatively, sort of a decent summary or have
Speaker:I, did I miss anything at all?
Speaker:Yeah, well, one of the things I didn't mention is that when you
Speaker:get this oxidative damage and or low a TV production, you have.
Speaker:Changes in the expression, the methylization and the aging of the
Speaker:cell and the protein management.
Speaker:You know, you're supposed to clear unfolded proteins and do all that stuff.
Speaker:All that kind of cell aging gets out of control and you get epigenetic changes
Speaker:and the cell starts acting differently.
Speaker:So sometimes it turns cells like a normal epithelial cell into a bone
Speaker:producing cell and starts causing calcifications of other kinds because
Speaker:you've messed up the genetic expression.
Speaker:So the cell gets confused about what kind of cell it is, goes through
Speaker:these, and it turns on cytokines that just promote that process.
Speaker:So the cytokines come along to deal with the crystals that are forming
Speaker:in those tissues along with these, this basic oxalic acid interfering
Speaker:with the mechanism of the factory.
Speaker:But you've also got this crystallization bringing in
Speaker:additional inflammation because inflammation comes in when the cell.
Speaker:The system detects this leakage of potassium and other problems with the
Speaker:cell, with the membrane structures.
Speaker:It comes along to try to get rid of the broken cell.
Speaker:And that broken tissue creates a room for, um, crystallization because
Speaker:the cul debris stimulates more precipitation of acid into crystals.
Speaker:And then you get crystal adhesions, and now you have more cytokines
Speaker:coming in trying to fize and get rid of these crystal accumulations.
Speaker:And that additional work by the cells turns on the kind of damage that causes
Speaker:cells to go from normal good cells to problematic bone cells and other
Speaker:cancer cells and things like that.
Speaker:Yeah, no, it, it.
Speaker:Yeah, it, it basic.
Speaker:Basically what you're doing is you are just creating cellular dysfunction
Speaker:at such a high level that these poly or mitochondria are almost
Speaker:completely unable to produce energy.
Speaker:Um, I'd, I'd, I'd like to sort of go, uh, take a bit of a, a stab at, uh, to,
Speaker:um, conditions that I think and are.
Speaker:And I think Oxidate based on my sort of, and uh, uh, reading of the literature,
Speaker:and this is obviously not my field, there definitely could be a very
Speaker:strong oxalate, uh, aspect to this.
Speaker:Uh, number one being hypothyroidism.
Speaker:Mm-hmm.
Speaker:And number two, being broadly speaking, cognitive decline.
Speaker:Mm-hmm.
Speaker:Your, uh, dementia dementias, your Alzheimer's, et cetera.
Speaker:Mm-hmm.
Speaker:Um, I know I've heard you talk about, uh, this before e especially
Speaker:with regards to hypothyroidism, but could you maybe briefly
Speaker:explain the link between, um, yeah.
Speaker:Sort of oxalate overload and then, uh, these, uh, these, these conditions?
Speaker:Yes.
Speaker:The oxalate overload is, so we have diets overload with oxalate, and
Speaker:we're eating enough of this acid.
Speaker:It's getting into your bloodstream to a level that is not only
Speaker:damaging the vascular system and the cells in there, but it's really.
Speaker:Stressing the excretion capacity of the kidneys and the kidneys are
Speaker:the last tissue to see oxalate.
Speaker:Yeah, because it's coming first in your gut, then getting into your vascular
Speaker:system, which goes straight to your liver.
Speaker:So now the liver has this open sinusoidal structures because the liver
Speaker:is, is filtering everything coming through and transforming nutrients
Speaker:and catching any problematic things.
Speaker:And it's being, all these cells and liver are wide open, exposed to the
Speaker:oxalic acid that was in your spin it smoothie and your, and your, you know,
Speaker:quinoa bread and your almond, whatever.
Speaker:I mean your chia bowl.
Speaker:Whoa.
Speaker:After each meal, even just, um, hash browns and chips and fries kind of stuff.
Speaker:You're loading up that liver, using up glutathione, and potentially
Speaker:leaving enough oxalate behind where you get some accumulation.
Speaker:But most of it's gonna leave the liver.
Speaker:And you know what else happens in the liver is that's where this
Speaker:endogenous production is occurring.
Speaker:So the liver is adding more oxalate to that blood.
Speaker:So the blood that leaves the liver could even have more oxalate than it
Speaker:had when it started from your geo bowl.
Speaker:And it goes just a few inches up to your heart.
Speaker:So now that blood is flowing through your heart and then it goes into your
Speaker:lungs and it flows through your lungs, and then it flows back into the heart
Speaker:and down into peripheral circulation.
Speaker:Well, it's gets everywhere and it gets into glands like the thyroid
Speaker:gland, the pancreas, the pituitary.
Speaker:You know, glands seem to pick up oxalate connected tissue, picks it up.
Speaker:Tissues that have a lot of, uh, calcium handling, like the bones and the breasts.
Speaker:The breasts make milk.
Speaker:So those cells have a special affinity for handling and concentrating calcium.
Speaker:And so it accumulates in the thyroid gland almost universally.
Speaker:By the time you're middle age, you have an 85% chance of having
Speaker:detectable visible levels of crystals.
Speaker:Like it can be so small, it's almost undetectable, but it's there.
Speaker:So it is, but a detectable that's really quite something.
Speaker:And it's also collecting in other tissues as well.
Speaker:Your eyes, your brain, the meninges around your brain, that's the
Speaker:sheaths, the your teeth, your jaws, your sinuses, your bone marrow.
Speaker:And so this stuff is damaging the function of these tissues.
Speaker:And in the thyroid thyroid's not a huge thing.
Speaker:Very busy, important master gland.
Speaker:You could be interfering, like we just said, the energy production makes
Speaker:it harder to produce enough thyroxin or you know, various hormones that
Speaker:it's producing and you are seeming to collect it there and that the crystal
Speaker:accumulation increases inflammation.
Speaker:So you have sort of a Hashimoto's like kind of pattern 'cause you're
Speaker:bringing in inflammation to deal with this oxalate collection.
Speaker:So there's no question that oxalate is a major player in this.
Speaker:Now epidemic of thyroid problem, thyroid illness, and neurological damage.
Speaker:It's very much a neurotoxin, it collects in the brain as well.
Speaker:Yeah.
Speaker:I suppose that sort of really could, uh, explain some of the etymology behind a
Speaker:disease like multiple sclerosis as well.
Speaker:I think we just, you you touched on, uh, nerve degen, myelin degeneration, e
Speaker:uh, earlier this, uh, idea that within multiple sclerosis anyway, that it's a
Speaker:disease whereby the myelin sheathing, uh, sheath, the fatty sheath thing
Speaker:that surrounds nerves, starts to break down, exposing those nerves to, to
Speaker:oxygen, to blood, which then causes, uh, such of die off within, within brain
Speaker:cells, within nervous system tissue.
Speaker:Um, so yeah, I, I, I, I, that's a great
Speaker:example of tissue maintenance problems.
Speaker:The cells that keep and maintain that insulation and people may not realize,
Speaker:you know, if you think of a, a cord that you use to plug something in.
Speaker:Underneath this vinyl is the, the charge where all the
Speaker:electrons are running through.
Speaker:So nerves kind of need this vinyl around them to function properly,
Speaker:and that's that myelin sheath.
Speaker:And when it goes away, woo, you don't want that kind of
Speaker:exposure to this, um, electricity generation process and vice versa.
Speaker:So the tissue maintenance occurs on nerves as well as connective tissues
Speaker:and other tissues as well, where you've got an energy deficit and you
Speaker:have a toxicity, and then you have inflammation coming into those tissues.
Speaker:So those cells that are, whose jobs are to maintain that tissue, can't do
Speaker:their job because they're so damaged.
Speaker:Yeah.
Speaker:You just, you just completely create this sort of dysregulation, this sort of excess
Speaker:sort of allosteric load within the body that just causes this complete shutdown
Speaker:of all these systems and, uh, yeah.
Speaker:No, it's, well, even
Speaker:incomplete shutdown is enough.
Speaker:It doesn't even have to be complete.
Speaker:In fact, a lot of this is happening under the hood where
Speaker:you feel fine until you don't.
Speaker:Like there's a breaking point, like it can be going on.
Speaker:Disease is often asymptomatic, meaning you have to have some way to measure
Speaker:the disease process, you know, a blood pressure cuff or something to be
Speaker:able to even detect what's going on.
Speaker:And so the body tries real hard to look good, even if under
Speaker:the hood things are rough.
Speaker:And so that's, it doesn't need to be complete breakdown.
Speaker:And I think it's important to pause on this because in the literature
Speaker:we often look at the fatal dose.
Speaker:Well, it takes five grams to die from it.
Speaker:So it's okay, well wait a minute.
Speaker:What if I just feel like I'm dying?
Speaker:Isn't that bad enough?
Speaker:Do I have to actually die to prove that I'm poisoned?
Speaker:Yeah.
Speaker:No, I don't think so.
Speaker:Yeah, no, thank you for, uh, for catching that.
Speaker:No, it, it's definitely, uh, an important point to remember, uh, which really
Speaker:sort of is, is quite a nice segue to my next question, um, really, which is
Speaker:about how to identify whether or not it's necessarily an oxalate tissue.
Speaker:Um, uh, I mean.
Speaker:Yeah, if you don't mind, I'll, I'm just gonna throw my, uh, six pence
Speaker:worth into the, into the conversation.
Speaker:Great.
Speaker:And, and I understand that oxalates are an issue, es especially if there's
Speaker:a ge, a genetic predisposition.
Speaker:However, uh, I'm also aware that there are a bunch of other potential
Speaker:triggers, uh, some of which are, are plants, defense chemicals, so your
Speaker:FODMAPs, your lectins, your tannins, uh, and then you obviously have, uh,
Speaker:o other issues, um, just, uh, your, your proteins and your simple sugars.
Speaker:Uh, your, uh, lic
Speaker:acid.
Speaker:Yeah.
Speaker:Cain, lactose, your, all of that.
Speaker:So, I suppose my question is there, especially from a, a plant defense
Speaker:mechanism standpoint, which I, I suppose is, is apt because that's
Speaker:the conversation we're having today.
Speaker:How can you be sure that it is a, an oxidative issue?
Speaker:I, I suppose at the end of the day, versus.
Speaker:A screaming case of you've just eaten too much cabbage and your
Speaker:fob maps are through the roof.
Speaker:Right, right.
Speaker:So again, there's lots of different angles on this and different
Speaker:stages of when this is relevant.
Speaker:I, I would say on the, the side of, am I getting sick with something
Speaker:and what's making me sick on the, on this kind of progression towards
Speaker:illness, what was causing it?
Speaker:I'd say the biggest, um, collaborator with oxalate to, to
Speaker:really get you is the lectins.
Speaker:And so if you have a high lectin, high oxalate diet that will get you
Speaker:period, it will eventually get you.
Speaker:I just feel so strongly about that, that Yeah.
Speaker:And even if it doesn't get you, it doesn't mean that it's safe.
Speaker:So this is another principle that goes with this just on this.
Speaker:The first side is the end side.
Speaker:Like, oh, you're sick and now what do you do?
Speaker:And now you've done something.
Speaker:How do you know oxalate was the reason you're better?
Speaker:But on this.
Speaker:Coming into the disease side,
Speaker:you have to remember that toxins that cause disease don't cause
Speaker:the same disease in the same amount of time in every person.
Speaker:So if you think about tobacco exposure or the use of cigarettes, and that's
Speaker:a broader form of toxicity because the filters and the chemicals and the other
Speaker:things done when you make a cigarette adds to the possible and very well
Speaker:documented toxicity of smoking cigarettes.
Speaker:So we put warning labels on cigarettes and we restrict who can buy them and we add
Speaker:taxes to them to make an incentive for you to not use this product because we know
Speaker:it can cause problems like lung cancer.
Speaker:But does every smoker die of lung cancer?
Speaker:They do not.
Speaker:Very few, very few people who smoke die of lung cancer, very few.
Speaker:So does that mean we should all just smoke cigarettes and ignore that toxin?
Speaker:Apparently it doesn't mean that, but people use that logic when they
Speaker:think about something like oxalate.
Speaker:Well, uncle Charlie's been eating X, Y, Z his whole life and he's still cutting
Speaker:down trees and he's 78 years old.
Speaker:Okay, so therefore you can pick out on it or let your pregnant daughter do that,
Speaker:or let your child have it as baby food.
Speaker:I don't think so, because when something is toxic, it is toxic,
Speaker:and you cannot predict who can withstand the toxin and who cannot.
Speaker:So you wanna use a precautionary approach and say, you know what?
Speaker:We should find out what generally is a tolerable level of a toxin
Speaker:and try not to exceed that.
Speaker:And that's my whole message with my book is that.
Speaker:We're built to handle a hundred milligrams or maybe 200 milligrams max a day.
Speaker:But most of you're eating 600 or a thousand.
Speaker:And those of you on spinach, you could be doing 3000 a day.
Speaker:And if you're a sick, frail person or a little baby, you literally could
Speaker:kill somebody with that or give them permanent health problems with thyroid
Speaker:dysfunction and even, um, fibrosis of the lungs because the lungs will try
Speaker:to help the poor kidneys get rid of it.
Speaker:And the lungs is in that first three organs that get slammed with it after
Speaker:each meal, so you can get in trouble.
Speaker:So I just wanna say like, is it oxalates?
Speaker:Well, something that's toxic ought to be on our radar period.
Speaker:Now when you're sick like I am and you finally do a low oxalate diet, when
Speaker:it's oxalate, at some point you start to see the body expelling the oxalate.
Speaker:So you will see it as cloudy urine.
Speaker:Tartar on the teeth, gritty stools, uh, skin breakouts.
Speaker:Some people literally get boils that push out whole crystals.
Speaker:Other people start snowing with white dust coming off their
Speaker:skin periodically or constantly.
Speaker:Some people constantly for years, and you can tell, oh my gosh, I
Speaker:have oxalate overload and now my overloaded body is puking it up all
Speaker:over the place and you can see it.
Speaker:So you can detect this oxalate overload with the deaccumulation process.
Speaker:And the other way you know it's oxalate is 'cause when you change your diet,
Speaker:suddenly wonderful things can happen.
Speaker:You sleep better.
Speaker:You aren't running to the bathroom all night long, your
Speaker:bladder's functioning better.
Speaker:You stop getting bladder infections, you stop getting yeast infections, you stop
Speaker:getting sinus infections, your vision gets better, your hearing is better.
Speaker:Your teeth stop hurting, like something good can happen when you
Speaker:quit poisoning your body, it's.
Speaker:You can kind of tell the, the confusion is that people think, well,
Speaker:there's probably something else.
Speaker:But once you get a toxin, that's also making you nutrient deficient
Speaker:by the way, in minerals and so on.
Speaker:Once you lower your exposure to this toxin and you, it helps your whole
Speaker:mitochondrial system, your, your barrier function of your epithelial tissues, all
Speaker:these things start functioning better.
Speaker:And the other problems like your mold and this and that,
Speaker:start clearing themselves up.
Speaker:That's interesting.
Speaker:Little bit off script and probably maybe a slightly technical question.
Speaker:Uh, is there like a relationship, you mentioned yeast, so you just
Speaker:put, am I, uh, uh, I got interested.
Speaker:Uh, is your relationship between oxalates and uh, fungal infections
Speaker:like candida, do you think
Speaker:Yes.
Speaker:That oxalates make you vulnerable to these infections?
Speaker:Not that they're producing the oxalate necessarily.
Speaker:There is a slight chance that some bacteria.
Speaker:That are related to candida or they're promoted by a candida infection,
Speaker:might produce a little oxalate.
Speaker:But what's happening is that the oxalate is wrecking your barrier
Speaker:function and your immune function and your sitting duck for infections.
Speaker:It also causes acidity and pH problems, and that promotes, um, an environment
Speaker:that allows these infections to occur.
Speaker:Yeah, no, that, okay, that makes total sense.
Speaker:I'll do some more research on that ortho there.
Speaker:But no, it was just something that, uh, just struck me as
Speaker:being a potential length there.
Speaker:Uh, there's only
Speaker:certain, there's only certain molds that produce oxalate and
Speaker:most of them are soil molds.
Speaker:And candida is a yeast that is not known to produce any oxalate.
Speaker:So it's not a direct, it's the other way around.
Speaker:It's that oxalates help create an environment where
Speaker:you get candida infections.
Speaker:Okay.
Speaker:I've learned something.
Speaker:Thank you.
Speaker:Yeah.
Speaker:Um, I suppose sort of the natural progression of this question
Speaker:would maybe be to talk about something like oxalate testing.
Speaker:Um, there are a bunch of different options out there.
Speaker:You, you get serum and urinary direct sort of, uh, test look at, uh, on oxalate.
Speaker:And then you've also got your organic acids tests that are looking
Speaker:at urinary oxalate metabolites.
Speaker:Um, do you think that these tests are, are clinically useful for individuals,
Speaker:uh, from a clinical point of view?
Speaker:Maybe helping them to sort of identify, um, whether oxalates are, again, are,
Speaker:are, are maybe for them genetically more of an issue than for somebody else?
Speaker:Um, do you think that Yeah.
Speaker:Do you think that they're useful in that they have a, a purpose or again, is it.
Speaker:Are oxalates sort of detrimental to the point where we should all
Speaker:just be eliminating as much of them from our diets as possible?
Speaker:Uh, as a general of thumb, if you get my understanding there.
Speaker:Right.
Speaker:So there's again, different agendas at play and how important testing is.
Speaker:Culturally testing has become very important.
Speaker:Patients want some validation that says, here, see this is really
Speaker:a real thing and see it's in my urine and it's seriously high.
Speaker:And that gives them, um, a pass for not being nuts with their husbands or their
Speaker:children or their doctor or something.
Speaker:So patients want that validation because they wanna know something
Speaker:really concrete and physical is wrong with them, rather than being
Speaker:told they're just anxious and crazy.
Speaker:So it has that value potentially if you don't get the false negative results.
Speaker:But I, for example, when I did the organic acids test in 2009, had
Speaker:absolutely no oxalate problem whatsoever.
Speaker:According to the test.
Speaker:Not anything was showing up, nothing completely clean.
Speaker:Bill of Health, I was so poisoned with oxalate and had been most of my life.
Speaker:And yet the test doesn't catch it.
Speaker:And this is the problem with assuming that biology is like an object on the desk.
Speaker:You cannot, you cannot expect your urine to, to be like a pen.
Speaker:That never changes except for the, it comes out, it's constantly
Speaker:in flux based on all kinds of metabolic priorities going on.
Speaker:The kidneys are very active.
Speaker:It's not just a blood filtering system.
Speaker:It's a whole, um, management of your metabolism going on with kidneys.
Speaker:There, there are major drivers of metabolism, major communicator about
Speaker:what's going on in the body, and they wanna do different things at night
Speaker:versus the morning versus after meals, versus in the spring or during Equinox.
Speaker:Like there's a lot going on.
Speaker:That causes a lot of variability.
Speaker:And one of the main things that the body does is help the kidneys not be constantly
Speaker:abused by too much oxalate all the time.
Speaker:So literally there's kind of like weekends where you get a little break and that
Speaker:break might always be at 10 in the morning when you took your test or something.
Speaker:Like there's these cycles going on, which we don't have a clue
Speaker:how this is so complicated.
Speaker:Maybe some SU supercomputer in the future will get a better sense
Speaker:of how the body is so brilliant.
Speaker:But to take a static test and say, oh no, oxalate problem, you can't do that.
Speaker:Now if you get a test that shows elevated oxalate and EL elevated
Speaker:all kinds of stuff that's oxalate metabolism related, then you wanna
Speaker:really believe that that is for real.
Speaker:Yeah, yeah.
Speaker:No, it's uh, yeah.
Speaker:So essentially it's not really.
Speaker:Let me see if I can get this right.
Speaker:You're not likely to get a, a false negative, but you should likely to get
Speaker:a, a false negative, a real positive, but you should not ignore a false positive.
Speaker:Positive.
Speaker:Don't ignore it.
Speaker:If you
Speaker:don't get a positive, you don't necessarily know anything.
Speaker:Yeah, that, that's fair enough.
Speaker:No, I, you can't
Speaker:like eliminate an oxalate problem by a test.
Speaker:Alright?
Speaker:Yeah.
Speaker:You can only
Speaker:eliminate an oxalate problem by doing the diet correctly, long enough.
Speaker:To see if it's making any difference.
Speaker:Yeah.
Speaker:And, and just out of interest, um, well actually, you know what, we
Speaker:can tie that into the next question, um, which I suppose sort of brings
Speaker:us around to sort of how to start getting, uh, rid of ox isolate safely.
Speaker:I know you, we've already, you've already touched on that with regards to sort of
Speaker:oxalate dumping and the fact that, um, if you do it potentially too quickly,
Speaker:maybe you can al almost end up with these, well, you can end up with these
Speaker:sort of her summer esque like reactions where the body actually starts to excrete
Speaker:oxalates every which way, uh, possible.
Speaker:And that can, as you mentioned earlier, sorts of, uh, manifest as, as skin issues
Speaker:as a worsening of current symptoms.
Speaker:Um, what in your mind, I suppose, no, not in your mind, um, it's a bit generic.
Speaker:You are the expert here.
Speaker:How would you.
Speaker:Um, counsel, an individual who has a high oxalate level to start weaning
Speaker:down and reducing the level of oxalates in their body so that they don't
Speaker:necessarily have these sort of very adverse reactions or those to some extent,
Speaker:uh, can you not get away from them?
Speaker:Well, first of all, you have to accept that this is a learning process.
Speaker:It's an education process.
Speaker:You have to get educated.
Speaker:You have to take the time to learn, and you can't just be given three tips and
Speaker:you're ready to roll and get in action.
Speaker:With ignorantly you, you don't wanna be a soldier following orders.
Speaker:You wanna be a informed person.
Speaker:So you're gonna need to take time to even examine your diet and think about, well,
Speaker:how much potatoes you've been eating.
Speaker:If you're using too much quinoa, beets, or these dark leafy greens,
Speaker:these three ones that are high in Oxley, other ones are fine, but
Speaker:you need to get to know the data.
Speaker:And you can't just do a Google search because there's a lot
Speaker:of bad stuff on the internet.
Speaker:I do have some free stuff on my website, toxic Superfoods.
Speaker:The book has many lists in there that are simple, and if you want detailed
Speaker:data, I've assembled it in a book you can buy just on my website, and you
Speaker:can learn and you can get a quick sense of like what things are high and low
Speaker:by just looking at the color coding.
Speaker:Things that are, uh, white, green, or yellow are fine, but the things
Speaker:that are in the darker orange in.
Speaker:Red are things you need to be really thinking about.
Speaker:Are you eating them?
Speaker:So you can think about your diet, what you've been doing recently,
Speaker:what you seem to like do doing, and find these worst offender foods and
Speaker:pick one that you can live without and learn how to live without it.
Speaker:Like Swiss chard who can live without Swiss chard, like get, just get practical.
Speaker:And so you start to learn what those are, and you start to be, 'cause you're
Speaker:modifying your shopping cart, your cooking habits, what you order when you eat out.
Speaker:Your whole life rhythm can be built around your meals and your meal prep
Speaker:and meal planning and your budgeting.
Speaker:So it's important to start thinking in that way.
Speaker:Like, how does a human being gradually change in their habits, in their thinking?
Speaker:So give yourself some patience.
Speaker:That's the main thing.
Speaker:I know we wanna just talk, well, you know, the science part and
Speaker:so on, but it's really important that you're a human being.
Speaker:And you are a microbiome, like you're also changing your microbiome whenever
Speaker:you change your diet in any way.
Speaker:And the more gently you can do that, the better.
Speaker:Now your body's been dealing with every meal you've been eating, some probably
Speaker:oxalates at most meals, and these waves of meals are keeping your blood level high.
Speaker:And when you start taking these foods out, the amount of oxalate
Speaker:in your bloodstream comes down.
Speaker:If it comes down really abruptly, the body can hear.
Speaker:That's a signal, right?
Speaker:That's a signal.
Speaker:Big high oxalate.
Speaker:Very little oxalate.
Speaker:And you stay little oxalate for just three days.
Speaker:It's all it takes for the body to go, oh, the bloodstream is open.
Speaker:It's an open, it's open area.
Speaker:We can now get it out of the thyroid gland.
Speaker:Yay.
Speaker:And then you bring in inflammation and try to bring on a thyroid gland.
Speaker:So you look at your worst offending foods and decide that you can live without
Speaker:peanut butter, Swiss chard, almonds, almond milk, almond, this and that.
Speaker:Cashews, fake cashew cheese.
Speaker:And you keep picking them off one by one.
Speaker:And basically you wanna get a sense of, well, wow, I've been eating over
Speaker:800 milligrams on a typical days.
Speaker:And on days when I do my double fudge whatever brownies, I'm at 1500 and
Speaker:on the days I do my spinach smoothie on Saturday mornings, I'm at 2,500.
Speaker:Like, then you can just knock off the 2,500 days.
Speaker:You wanna get out of that toxic danger zone of a consumption and bring it down.
Speaker:And if even if you bring it down to like 200, even 400, you can start to benefit
Speaker:without maybe, um, inspiring a riot.
Speaker:You might say, the teacher's like, yeah man, we could get rid of this stuff.
Speaker:You don't really, you want, it's better to leave all this accumulation where it
Speaker:is and just stop accumulating and stop flushing all your organs in your vascular
Speaker:system meal after meal after meal.
Speaker:And you could do it another way.
Speaker:You could do it or just say, I wanna make sure.
Speaker:Every breakfast is oxalate free, or every dinner is is low oxalate.
Speaker:Um, and learn how to do that.
Speaker:So there's a, there's a whole individual process, like what works for your
Speaker:lifestyle, your personality and your family, how you actually do it.
Speaker:But what all you need to know is that this is not a hundred percent elimination diet.
Speaker:This is not a gluten-free allergy thing whatsoever.
Speaker:This is about toxicity.
Speaker:You have to get out of that really toxic zone.
Speaker:And so that means almost any high oxalate food could be reintroduced
Speaker:because you could go back to having hot cocoa if all the other
Speaker:oxalate foods are outta your diet.
Speaker:There's room for any of them, but just get rid of the ones you know you can
Speaker:live without, and then start getting.
Speaker:Uh, gradually moving towards a, a sensible diet that's gonna work for you,
Speaker:hopefully not triggering the excessive deaccumulation that can be create an
Speaker:illness because you could literally cause disruptions in the ions in your blood.
Speaker:'cause you're putting acid back in your blood.
Speaker:You drop the calcium levels as it grabs that calcium.
Speaker:You have hypocalcemia, which can cause pacemaker problems, arrhythmias,
Speaker:super spikes, and hypertension.
Speaker:And you feel like you're having a heart attack because you're
Speaker:having electrolyte crises.
Speaker:You may be acting like you've had a stroke and dragging your left side around.
Speaker:Uh, it can get really serious when you mess up your blood electrolytes
Speaker:and have this inflammation going on at the same time.
Speaker:Yeah, I, I suppose, well, what I've taken from that is age,
Speaker:it, it probably shouldn't be sort of this binary execution.
Speaker:IE don't just jump straight onto a carnival diet if you think
Speaker:you've got an oxid overload.
Speaker:Uh, and B um, yeah, as you've, uh, just alluded to.
Speaker:Yeah, just take it slowly.
Speaker:Um.
Speaker:Supplements, I think.
Speaker:Uh, you mentioned calcium.
Speaker:Um, the other one that springs to mind is vitamin B six, um, which I
Speaker:know is involved in the clearance of, of, uh, oxalate, specifically BB six.
Speaker:If I, my biochem is correct.
Speaker:I think it helps convert gly oxalate into glycine instead of oxalate.
Speaker:I think, uh, right back
Speaker:and forth, it's, I think it's on both enzymes.
Speaker:It can turn glycine to oxalate or turn oxalate back into glycine.
Speaker:Okay.
Speaker:Um, and, or, you know, hydroxyproline, which is more likely, but you also have
Speaker:B one or thiamine is turning oxalate into non-toxic chemicals without
Speaker:enough B one, well, not oxalate.
Speaker:See, what we're, the mistake we're making is, is this, this precursor to oxalate,
Speaker:this precursor, there's actually three glyoxal, oxalate and so on that are
Speaker:in there that are toxic in themselves, acidifying themselves, but there.
Speaker:There are precursor these, these enzymes can shunt that and protect
Speaker:that from becoming all oxalate.
Speaker:If you have the co-factors, that's what vitamins are.
Speaker:They're co-factors on the enzymes that make metabolic transformations
Speaker:in turn one molecule into a different kind of molecule.
Speaker:So you need these B vitamins on these transforming proteins so
Speaker:they can protect us from excessive production of oxalate in cells.
Speaker:Um, the liver, the kidney and red blood cells are may
Speaker:mostly where this is happening.
Speaker:That doesn't really protect you from the excessive vitamin C that can just turn
Speaker:into oxalate without even enzymatic.
Speaker:Both vitamin C, there's both enzyme pathways that turn it into
Speaker:oxalate and there's just transfer, just spontaneous, like literally
Speaker:in a vitamin bottle of vitamin C.
Speaker:It can turn into oxalate just sitting there.
Speaker:Um, so the vitamin C is interesting because it gets into all cells.
Speaker:And if any cell in the body can accumulate vitamin C and start
Speaker:having oxalate formation in the cell with or without the enzyme.
Speaker:So that's where the B vitamins are not protecting you from
Speaker:that vitamin C necessarily.
Speaker:So yeah, the supplements are very important.
Speaker:We've now created a mineral deficiency by overeating oxalate, and calcium is
Speaker:the binder that helps you remove oxalate from the body safely and gives it a whole
Speaker:lot of buffering capacity to handle these wobbling hypo calcium attacks that happen
Speaker:as your body's trying to release oxalate.
Speaker:So you need a lot of calcium, and the supplement form is
Speaker:excellent for doing this.
Speaker:It is the number one medicine for people who are oxalate poisoned, does not
Speaker:cause calcification of your arteries.
Speaker:Calcification of the body is because of what we talked about
Speaker:before where the cells are damaged and now they're turning into bone
Speaker:cells, and that's the damage side.
Speaker:The calcium helps prevent further damage that the supplement calcium,
Speaker:so alkaline minerals, with calcium being the main one, potassium is being
Speaker:leaked out and lost in the process.
Speaker:So potassium's very important.
Speaker:Most people are deficient in it.
Speaker:Usually we, there's a need for magnesium and often we like to
Speaker:see these in a citrate form.
Speaker:You can also use some of them in a bicarb form because there's a lot of acidity
Speaker:going on, and the alkaline minerals help address some of that acidity.
Speaker:The bicarb helps doing that.
Speaker:And then there's citrates.
Speaker:So citric acid comes from lemon juice, but we also use citrates to deliver
Speaker:these minerals and supplement forms.
Speaker:So often we suggest you start with the citrate form of.
Speaker:At least the calcium or the um, you can do that with magnesium as well and so on.
Speaker:But you can play around because it's a separate issue.
Speaker:But the citrate prevents crystal growth and helps the hard crystals that are
Speaker:hard, like quartz, it softens them because citric acid has such a strong affinity
Speaker:for calcium that it's even stronger than the oxalate affinity for calcium.
Speaker:So when it sits on a calcium oxalate molecule income citrate, it actually
Speaker:loosens the bond between oxalate and calcium and makes it more chalky, softer,
Speaker:and then you can break it down easily.
Speaker:So it destabilizes that sort of crystal light, obviously
Speaker:cleaved off.
Speaker:Yeah.
Speaker:Crystal.
Speaker:Yeah.
Speaker:So it's really just weakening the bonds.
Speaker:Yeah.
Speaker:But it turns quartz into chalk so you can get rid of it.
Speaker:So the citrates are really great and.
Speaker:Um, when the cells have the right pH they can generate citrate themselves and the,
Speaker:the urine needs to be high in citric acid.
Speaker:That would be a good test to run, is how much CI citrate your kidneys
Speaker:can put out, um, because that's protecting you from kidney stones.
Speaker:So if people with a history of kidney stones, we might look at that.
Speaker:Um, so those are the main things where you can use B vitamins,
Speaker:the minerals and citric acid.
Speaker:Those are the main ones.
Speaker:And then there's other things that can help along the way comes to
Speaker:EDTA, et cetera.
Speaker:Yeah, and just, just generally supporting the damage nervous system with things like
Speaker:choline or, it depends on that person's issues, but e even, you know, occasionally
Speaker:needing aspirin, things like this 'cause there's so much inflammation going on.
Speaker:So you need a little bit of support, but I like to use.
Speaker:Is few oral things.
Speaker:You can even use mineral baths and topical things to really support this
Speaker:process if people's, oftentimes you have problem with digestion with these folks.
Speaker:'cause you almost always have some digestive dysfunction, either because
Speaker:the nerves aren't working right and now the muscles of the sphincters
Speaker:are damaged in their function or the whole, um, many of the tissues
Speaker:in the gut are a little distressed.
Speaker:There's, there's immune tissues and just the general absorptive
Speaker:surface is, is not good.
Speaker:And then you have potentially some problems with bile production,
Speaker:uh, production of anything from the pancreas, including your
Speaker:insulin, but also the digestive.
Speaker:Enzymes and so on.
Speaker:So it depends on what's going on, what other supplements might be useful.
Speaker:Yeah, and I think what's important to take away for the listener is that,
Speaker:uh, what, what you've just alluded to can does and can get very complicated.
Speaker:But at a high level, if you just start to slowly reduce the total oxalate,
Speaker:uh, your total oxalate intake, you are very likely to sort of resolve
Speaker:the majority of these issues without necessarily needing to get to this point.
Speaker:Especially if you're still in the, in, in the state where you are
Speaker:not feeling a hundred percent, but you're not necessarily in that.
Speaker:Um, I can't get out Bed Point.
Speaker:The earlier the better.
Speaker:Yes, of
Speaker:course.
Speaker:So
Speaker:because this is really, those of us who've really messed up our lives with oxalate
Speaker:would, would just wish to not have anyone go through what we've been through.
Speaker:This can be very devastating and bring people to the brink of
Speaker:serious problems that could be.
Speaker:Yeah.
Speaker:Very hard to live with.
Speaker:And the, the recovery process is not quick.
Speaker:It might be 10 or 15 years of recovery.
Speaker:Yeah, no, um, yeah, you, you, you've got to rebuild the body
Speaker:at, uh, at a cell by cell level.
Speaker:Yeah.
Speaker:Um, Sally, I know we're starting to run short on time, but sort of
Speaker:end off with, I'd love to ask you just a few rapid ish fire questions.
Speaker:These never end up being rapid fire, but we'll try, we'll do our best.
Speaker:See
Speaker:if we can win the game.
Speaker:Yeah.
Speaker:We'll, we'll do our best.
Speaker:Um, the first one is going to be about as rapid as my, as I am first thing
Speaker:in the morning with our caffeine.
Speaker:Um, but, and this is, is something we had discussed previously, but
Speaker:why isn't this a bigger issue?
Speaker:Uh, why isn't this being, uh, sort of looked at?
Speaker:More at, at a more institutional level.
Speaker:Um, why is it being swept on the rug?
Speaker:And I, I'm sure we could get somewhat conspiratorial, but, um, at, at the, yeah.
Speaker:What are your thoughts on that?
Speaker:Well, the
Speaker:fast answer is read my book.
Speaker:There's a chapter on this and it talks about the failures in medicine and
Speaker:nutrition and so on of ignoring this.
Speaker:And some of it literally, the system is rigged to keep disease processes going
Speaker:because researchers need careers and you can't solve the problem you're, you're
Speaker:studying because then you're out of a job.
Speaker:Yeah, no, that makes total sense.
Speaker:Okay, nice and simple.
Speaker:Next one.
Speaker:Um, what's the one high oxalate food that's, uh, people would be
Speaker:surprised to learn is problematic?
Speaker:Well, buckwheat, quinoa, chia seeds.
Speaker:I would say most people are shocked at the spinach one, but anyone who knows anything
Speaker:about nutrition is not shocked about that.
Speaker:So if you're shocked, go back to 1 0 1 nutrition class 'cause
Speaker:hello and brand is another one.
Speaker:But brand was fashionable in the eighties, I guess it's a little
Speaker:fashionable again, but those are key ones.
Speaker:And I would say generally gluten-free stuff, almost always
Speaker:high oxalate and keto stuff.
Speaker:The chocolate and the, the almonds and so on.
Speaker:Yeah.
Speaker:Yeah.
Speaker:No, I, I was going to, I was, my pick for that would've been chocolate.
Speaker:I think most people ah, yeah.
Speaker:Get, get a nasty surprise when you say, uh, that 90% lin that you're eating.
Speaker:Yes.
Speaker:It's low in sugar, but it's
Speaker:high in lead.
Speaker:Cadium and oxalate.
Speaker:There we go.
Speaker:Yeah.
Speaker:But I try not to break that news because I don't wanna get hit or shot.
Speaker:Yeah, it's, uh, it's, you are dancing the fire a bit there.
Speaker:Um, well here's another one.
Speaker:Oh, another one.
Speaker:Let's,
Speaker:mm-hmm.
Speaker:Turmeric.
Speaker:Yes, of course.
Speaker:Yeah.
Speaker:And I think you can back up the whole word, turmeric, but yeah.
Speaker:Coaching co and
Speaker:extracts are not, yeah.
Speaker:So if you're interested in playing with the extracts, there are no problem.
Speaker:Perfect.
Speaker:Um, what's the most common misconception about oxalates that
Speaker:you encounter on a day-to-day basis?
Speaker:Oh, most common misconception about oxalates?
Speaker:Well, you have to have renal failure or kidney stones for it to matter.
Speaker:If you haven't had a kidney stone, you can have all you want.
Speaker:No, you have a lot of other tissues that care, including your precious teeth and
Speaker:your eyes and your thyroid gland, and your vascular system and your immune cells.
Speaker:Send your liver and a few other things.
Speaker:Your desire to live.
Speaker:Yes.
Speaker:Your
Speaker:desire to live and not be feeble and not be old before your time.
Speaker:Because I believe knowing about oxalate and getting 'em out of your
Speaker:life, you found the fountain of youth.
Speaker:Yeah.
Speaker:No, I couldn't agree more.
Speaker:And the last one, um.
Speaker:Maybe a bit of a controversial one and something we've already discussed
Speaker:in passing already, but what do you think about the carnivore diet,
Speaker:uh, in relation to all of this?
Speaker:The carnivore diet is an excellent demonstration of the need and value
Speaker:of meat products, meat in the diet.
Speaker:It's also a very handy elimination diet that'll help you, um, take a
Speaker:break from lots of chemicals and lots of confusion about what dietary things
Speaker:might be influencing your health.
Speaker:The thing is too long in a carnivore diet could actually increase your
Speaker:intolerance potentially if have oxalate poisoning to some plant foods.
Speaker:So I don't know if that's really true.
Speaker:We really need research on that.
Speaker:Um, and.
Speaker:It is essentially a zero carb diet and day in and day out.
Speaker:A zero carb is gonna be kind of rough.
Speaker:You're gonna have some degree of insulin sensitivity, so it's gonna take a while
Speaker:to get you tolerant to some carbs.
Speaker:Again, if you're needing to go back and diversify your
Speaker:diet, you need to be patient.
Speaker:But I, I really love that people seem to be thriving on carnivore because
Speaker:too many people are undereating protein guys who are working out like crazy.
Speaker:Mm-hmm.
Speaker:And aren't putting on bulk because they want only like
Speaker:three ounces of meat twice a day.
Speaker:That's not enough meat.
Speaker:Yeah.
Speaker:To me,
Speaker:I think you need five ounces, two or three times minimum.
Speaker:Like, I'd like to see people be more comfortable with meat and protein.
Speaker:Yeah, I think sort of aim for that one gram of, uh, protein per per
Speaker:kilogram, per pound of body, uh, weight is a reasonable assumption.
Speaker:Um, whether it's lean mass or not is up for debate.
Speaker:But yeah, no, I definitely, I couldn't agree more.
Speaker:The RDA on on protein is woefully low, and especially as we start looking
Speaker:at all the populations that already have protein malabsorption issues and
Speaker:assumingly, um, oxid issues like elderly.
Speaker:Yeah, yeah,
Speaker:for sure.
Speaker:Yeah.
Speaker:And I'm just shocked at how many people work out multiple times a
Speaker:day and they won't eat protein.
Speaker:Like, mm. You could look extra cute if you ate.
Speaker:Just don't eat the whole thing.
Speaker:Eat enough.
Speaker:So that's, um, the beautiful thing about carnivore is that people can pile their
Speaker:plates with animal foods and thrive on it.
Speaker:Yeah.
Speaker:It
Speaker:seemingly,
Speaker:uh.
Speaker:I, I'm, I'm definitely looking forward to seeing some longer term EC data there.
Speaker:Um, I mean, Reddit is obviously full of, um, and some, potentially some
Speaker:studies, but I think the anecdotal evidence will come first, um, of
Speaker:people who have been on this diet 5, 10, 15, 20 years, uh, en masse.
Speaker:I mean, obviously you've got your, your Sean Bakers of the world.
Speaker:Um, but I think they are more the exception than the rule.
Speaker:If I can interrupt you and say, the biggest downside of carnivore is
Speaker:that chronic ketosis means chronic low grade acidity, which breaks down
Speaker:your connective tissue and promotes osteoporosis and maybe cancer.
Speaker:So I really think you're gonna end up with connective tissue issues.
Speaker:Your old tennis elbow and your old football injuries are gonna come back
Speaker:and kick you hard if you're not at least correcting the pH and not getting
Speaker:enough minerals, and maybe even just getting outta ketosis once in a while.
Speaker:But I, I do think the downside of chronically using an
Speaker:elimination diet like that.
Speaker:Is, um, quite serious.
Speaker:If, again, if you wanna be fit and healthy, you may lose your
Speaker:ability to have a healthy joint.
Speaker:And bones.
Speaker:Yeah, in
Speaker:theory,
Speaker:I think some of that, and this has definitely turned into a
Speaker:very un rapid fire question.
Speaker:Um, sorry.
Speaker:No, it's my fault as well.
Speaker:Uh, could be mediated by that ingestion of protein and, and then the breakdown
Speaker:or that protein into sugar through gluconeogenesis and all of that.
Speaker:But no, fundamentally, I do completely agree with you.
Speaker:I, I think that, um, if you look at it sort of from an evolutionary
Speaker:anthropological, uh, sort of whatever term best, uh, you best identify with,
Speaker:um, viewpoint, you'll sort of note that people sort of ate seasonally.
Speaker:They went in and out of these, um, these dietary patterns.
Speaker:Uh, nobody stuck to anything.
Speaker:Uh, at least again, based on my view of the literature, literature
Speaker:indefinitely, there was, there were always sort of shifts in
Speaker:and outta these dietary patterns.
Speaker:Um, which I think sort of speaks, speaks volumes to how we
Speaker:should eat, generally speaking.
Speaker:Anyway.
Speaker:Um.
Speaker:For this, uh, yeah, caveat being exclude Ox Oxfords.
Speaker:But yeah, Sally, um, you've been an absolute angel and a star and thank
Speaker:you so much for this conversation.
Speaker:Um, I have a feeling that this is a, a pretty easy one to answer 'cause
Speaker:all people really need is Google.
Speaker:But, um, where's the best place that people can find you?
Speaker:Sally key norton.com.
Speaker:Sally key norton.com is my website.
Speaker:There's a lot of free information there.
Speaker:There's free downloads.
Speaker:That's the only place you can get the data for oxalates.
Speaker:Don't try to get some knockoff off Amazon.
Speaker:Um, and you can find me on Instagram mostly for social media.
Speaker:I don't spend a lot of time on the other channels much, but
Speaker:I also have a YouTube channel.
Speaker:I really encourage people to come visit Sally k Norton, the,
Speaker:or It's SK Norton, either one.
Speaker:Uh, YouTube channel where we have testimonials.
Speaker:We have about 13 there.
Speaker:We have about 22 shorts.
Speaker:These are just little one minute videos and you may find one or two
Speaker:in there that will help you help somebody else discover this topic.
Speaker:Those little one minutes you could probably barter for
Speaker:one minute of someone's time.
Speaker:So, uh, hopefully you're using that YouTube video channel of
Speaker:mine to, uh, help other people
Speaker:of course benefit.
Speaker:Yeah.
Speaker:And we'll be sure to link to all of that in the show notes when
Speaker:the, the podcast is obviously live.
Speaker:Sally, thank you so much again.
Speaker:I really do appreciate it.
Speaker:Thank you.
Speaker:It's wonderful to be with you and I'm so glad your audience is gonna
Speaker:take an interesting in oxalate.
Speaker:Thank.